Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750054 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL12684655 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL29920 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL6692816 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL151903 | 0.91 | LMNA (0.40) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL1687120 | 0.90 | THRB (0.37) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL891846 | 0.88 | LMNA (0.41) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL6448213 | 0.88 | LMNA (0.41) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL2985499 | 0.88 | LMNA (0.41) | LMNAL3MBTL1TDP1THRBCYP2D6 | |
| SCHEMBL3168782 | 0.88 | LMNA (0.41) | LMNAL3MBTL1TDP1THRBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380462-B1 | METHODS FOR ANALYSIS AND RESOLUTION OF PREPARATIONS OF DIANHYDROGALACTITOL AND DERIVATIVES OR ANALOGS THEREOF | DEL MAR PHARMACEUTICALS BC LTD (CA) | 2021-02-17 | — | — | EP | disclosed |
| US-10591445-B2 | Methods for analysis and resolution of preparations of dianhydrogalactitol and derivatives or analogs thereof | DEL MAR PHARMACEUTICALS (BC) LTD. (CA) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10591445-B2 | Methods for analysis and resolution of preparations of dianhydrogalactitol and derivatives or analogs thereof | HEXD, GMDS, DDOST | LMNA 771/4885L3MBTL1 3077/4885TDP1 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.