Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887770 | 0.82 | NR1H2 (0.39) | NR1H2PTGS2RXRANR1H3 | |
| SCHEMBL21888601 | 0.81 | NR1H2 (0.42) | NR1H2PTGS2RXRANR1H3 | |
| SCHEMBL21887870 | 0.77 | ALDH1A1 (0.41) | FAAH | |
| SCHEMBL16566090 | 0.74 | NR1H2 (1.00) | NR1H2CA9CHRNA7PTGS2FAAH | |
| SCHEMBL21887871 | 0.71 | NR1H2 (0.43) | NR1H2RXRANR1H3 | |
| SCHEMBL17943801 | 0.69 | NR1H2 (0.91) | NR1H2CA9CHRNA7PTGS2FAAH | |
| SCHEMBL16566156 | 0.68 | NR1H2 (0.65) | NR1H2PTGS2 | |
| SCHEMBL16553489 | 0.67 | NR1H2 (0.77) | NR1H2CA9CHRNA7PTGS2FAAH | |
| SCHEMBL21887872 | 0.66 | NR1H2 (0.39) | NR1H2RXRANR1H3 | |
| SCHEMBL16452709 | 0.66 | NR1H2 (0.62) | NR1H2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |