Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888597 | 0.80 | HTR2A (0.31) | — | |
| SCHEMBL21887769 | 0.77 | NR1H2 (0.59) | FAAH | |
| SCHEMBL21887738 | 0.73 | HTR2A (0.32) | — | |
| SCHEMBL15868151 | 0.72 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2AGABRG2GABRB3 | |
| SCHEMBL21888596 | 0.72 | HTR2A (0.30) | — | |
| SCHEMBL21887773 | 0.71 | PTGS2 (0.34) | — | |
| SCHEMBL21607874 | 0.70 | FAAH (0.45) | ALDH1A1SMN1; SMN2KMT2AGABRG2GABRB3 | |
| SCHEMBL15868122 | 0.70 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2GABRG2GABRB3GABRA5 | |
| SCHEMBL24456863 | 0.70 | CYP1A2 (0.47) | ALDH1A1TDP2KMT2AMAPT | |
| SCHEMBL21598388 | 0.70 | MARS1 (0.47) | ALDH1A1SMN1; SMN2KMT2AFAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |