Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843323 | 0.90 | GRM5 (0.52) | GRM5ABCG2ABCB1KCNH2MEN1 | |
| SCHEMBL27220666 | 0.89 | ABCG2 (0.56) | GRM5ABCG2ABCB1MEN1ALDH1A1 | |
| SCHEMBL23384084 | 0.88 | ABCG2 (0.54) | GRM5ABCG2ABCB1MEN1ALDH1A1 | |
| SCHEMBL20793998 | 0.85 | GRM5 (0.46) | GRM5KCNH2 | |
| SCHEMBL3276483 | 0.84 | PGR (0.50) | GRM5TSHR | |
| SCHEMBL12551709 | 0.84 | GRM5 (0.43) | GRM5ABCG2ABCB1KCNH2 | |
| SCHEMBL12578707 | 0.83 | GRM5 (0.44) | GRM5KCNH2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL12551707 | 0.83 | GRM5 (0.43) | GRM5ABCG2ABCB1 | |
| SCHEMBL21461842 | 0.82 | L3MBTL1 (0.52) | GRM5ABCG2MEN1ALDH1A1LMNA | |
| SCHEMBL27095786 | 0.82 | L3MBTL1 (0.52) | GRM5ABCG2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056859-A1 | 9,10-DIHYDROACRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 宁波卢米蓝新材料有限公司 | 2020-03-26 | — | — | WO | disclosed |
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | DHODH, DHRS9, QDPR | GRM5 3107/4885ABCG2 447/4885ABCB1 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.