Water

Water

SCHEMBL218905

O.O=[N+]([O-])[O-].[Ni]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11146310 1.00
Water SCHEMBL11778926 1.00 MEN1 (0.67)
Water SCHEMBL6142507 1.00 MEN1 (0.67)
Water SCHEMBL10424730 1.00 MEN1 (0.67)
Water SCHEMBL987709 1.00
Water SCHEMBL229106 1.00 MEN1 (0.67)
SCHEMBL8999403 0.94 MEN1 (0.75)
Water SCHEMBL10566608 0.94 MEN1 (0.75)
Water SCHEMBL2590832 0.94 MEN1 (0.75)
SCHEMBL1121202 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076451-A Modified Ni/CeO2Preparation method and application of catalyst 2026-05-26 CN claimed
CN-122067922-A Porous electrode material, preparation method thereof and capacitor 深圳市力容电子有限公司 2026-05-19 CN claimed
EP-4691998-A1 METHOD FOR PRODUCING METAL OXIDE NANOPARTICLES, METAL OXIDE NANOPARTICLES, INK COMPOSITION COMPRISING SAME, LIGHT-EMITTING ELEMENT, ELECTRONIC DEVICE, AND ELECTRONIC APPLIANCE Samsung Display Co., Ltd. (KR) 2026-02-11 EP claimed
CN-120089743-A Composite positive electrode lithium supplementing additive and preparation method and application thereof 合肥国轩高科动力能源有限公司 2025-06-03 CN claimed
CN-120082920-A Ni/Ni (OH)2Preparation method of heterojunction nano electrocatalyst and application of heterojunction nano electrocatalyst in hydrogen production 江苏科技大学 2025-06-03 CN claimed
CN-119446800-B Sulfur-doped nickel-manganese layered double hydroxide electrode material, preparation method and capacitor 西安理工大学 2025-04-04 CN claimed
CN-119638542-A Catalyst for producing methane and preparation method and application thereof 中国石油大学(北京) 2025-03-18 CN claimed
CN-119591473-A Method for synthesizing glycol from hemicellulose 福州大学 2025-03-11 CN claimed
CN-115957763-B Methane synthesis catalyst and preparation method and application thereof 中石化南京化工研究院有限公司 2025-02-25 CN claimed
CN-119446800-A Sulfur-doped nickel-manganese layered double hydroxide electrode material, preparation method and capacitor 西安理工大学 2025-02-14 CN claimed
US-20070251351-A1 Nickel powder manufacturing method SHOEI CHEMICAL INC. (JP) 2007-11-01 US claimed
EP-1849540-A1 Nickel powder manufacturing method SHOEI CHEMICAL INC. (JP) 2007-10-31 EP claimed
CN-101062524-A Nickel powder manufacturing method SHOEI CHEMICAL IND CO (JP) 2007-10-31 CN claimed
WO-2005102043-A2 USE OF NICKEL TO CORRECT GROWTH DISORDERS IN PLANTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-11-03 WO claimed
US-20050245397-A1 Use of nickel to correct growth disorders in plants NIPAN, LLC 2005-11-03 US claimed
EP-0422105-B1 METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME BATTELLE MEMORIAL INSTITUTE (US) 1994-09-07 EP claimed
US-5114702-A Method of making metal oxide ceramic powders by using a combustible amino acid compound BATTELLE MEMORIAL INSTITUTE (US) 1992-05-19 US claimed
EP-0422105-A4 METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME 1992-01-08 EP claimed
EP-0422105-A1 METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME. BATTELLE MEMORIAL INSTITUTE (US) 1991-04-17 EP claimed
WO-1989012027-A1 METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME BATTELLE MEMORIAL INSTITUTE (US) 1989-12-14 WO claimed