Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265997 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2288874 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Potassium Ion SCHEMBL8715930 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Silver SCHEMBL218931 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2524420 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL214687 | 0.91 | KDM4E (0.62) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2521157 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Lithium Ion SCHEMBL1458081 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL11359480 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL29265992 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742136-B2 | Method for producing cyclic disulfonic acid ester | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2036899-B1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER | WAKO PURE CHEM IND LTD (JP) | 2011-11-02 | — | — | EP | disclosed |
| US-20090281333-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-2036899-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER | Wako Pure Chemical Industries, Ltd. (JP) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | KDM4E 934/4885MAPT 971/4885ALOX15 2763/4885 |
| US-20090281333-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER | STS, PDIA6, PDIA5 | KDM4E 4736/4885MAPT 4877/4885ALOX15 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.