Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545077 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2288874 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL11359480 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Silver SCHEMBL218931 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL214687 | 0.91 | KDM4E (0.62) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2521157 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL218933 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Lithium Ion SCHEMBL1458081 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2524420 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL29265990 | 0.91 | KDM4E (0.53) | KDM4EMAPTALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319014-A | UNDATURATED CARBOXYLIC ACID COPOLYMER WITH UNDATURATED SULFONATE COMONOMER MODIFIED BY A MERCAPTAN | UNIROYAL, INC. (US) | 1982-03-09 | — | — | US | claimed |
| US-12129239-B2 | Method for producing methylene disulfonate compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2024-10-29 | — | — | US | disclosed |
| EP-4006020-B1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2024-09-25 | — | — | EP | disclosed |
| CN-114144407-B | Process for producing cyclic disulfonate compound | 住友精化株式会社 | 2024-02-13 | — | — | CN | disclosed |
| US-11802119-B2 | Method for producing cyclic disulfonic acid ester compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2023-10-31 | — | — | US | disclosed |
| US-20220251059-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220251060-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2022-08-11 | — | — | US | disclosed |
| EP-4006020-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2022-06-01 | — | — | EP | disclosed |
| EP-4006019-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2022-06-01 | — | — | EP | disclosed |
| CN-114144407-A | Process for producing cyclic disulfonate compound | 住友精化株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-114144406-A | Method for producing methylene disulfonate compound | 住友精化株式会社 | 2022-03-04 | — | — | CN | disclosed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| EP-0029970-B1 | COPOLYMER USEFUL AS A SURFACTANT | UNIROYAL, INC. (US) | 1984-08-01 | — | — | EP | disclosed |
| US-4080358-A | PROPYLENE OXIDE ADDUCTS OF GLYCEROL OR POLYETHER | THE DOW CHEMICAL COMPANY (US) | 1978-03-21 | — | — | US | disclosed |
| US-3992333-A | NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER | ROHM AND HAAS COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3960584-A | CELLULOSE ETHER | THE DOW CHEMICAL COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129239-B2 | Method for producing methylene disulfonate compound | TST, MPST, SQOR | KDM4E 1409/4885MAPT 3739/4885ALOX15 1858/4885 |
| US-20220251060-A1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | STS, TST, SCLY | KDM4E 4069/4885MAPT 4459/4885ALOX15 1582/4885 |
| US-20220251059-A1 | METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND | TST, MPST, SQOR | KDM4E 1409/4885MAPT 3739/4885ALOX15 1858/4885 |
| US-11802119-B2 | Method for producing cyclic disulfonic acid ester compound | STS, TST, SCLY | KDM4E 4069/4885MAPT 4459/4885ALOX15 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.