Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BAX | Q07812 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455421 | 0.75 | LTA4H (0.50) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL2121427 | 0.71 | LTA4H (0.45) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL31509748 | 0.71 | LTA4H (0.45) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL10358829 | 0.71 | CA4 (0.48) | LTA4HTSHRCA4KCNA3TDP1 | |
| SCHEMBL28667326 | 0.71 | LTA4H (0.45) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL6911259 | 0.69 | LTA4H (0.43) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL18570099 | 0.69 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL10043046 | 0.67 | HSP90AA1 (0.44) | LTA4HTSHRCA4SRCCA5A | |
| SCHEMBL11032763 | 0.65 | L3MBTL1 (0.43) | LTA4HTSHRCA4SRCKCNA3 | |
| SCHEMBL10358464 | 0.65 | L3MBTL1 (0.45) | LTA4HTSHRCA4KCNA3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341915-B1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NAT RECH SCIENT (FR) | 2019-03-20 | — | — | EP | disclosed |
| US-10106565-B2 | Phosphorylated dendrimers as antiinflammatory drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-10-23 | — | — | US | disclosed |
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20130336997-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-19 | — | — | US | disclosed |
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |
| EP-2341915-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | Centre National de la Recherche Scientifique (FR) | 2011-07-13 | — | — | EP | disclosed |
| US-20100173871-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-08 | — | — | US | disclosed |
| WO-2010013086-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-02-04 | — | — | WO | disclosed |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-06-04 | — | — | US | disclosed |
| EP-1771548-A1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006024769-A1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10106565-B2 | Phosphorylated dendrimers as antiinflammatory drugs | DUSP6, DUSP10, PTMS | LTA4H 1210/4885TSHR 2547/4885CA4 4250/4885 |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | HDGF, CD40LG, PPIP5K2 | LTA4H 2271/4885TSHR 383/4885CA4 1673/4885 |
| US-20130336997-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | DUSP6, DUSP10, PTMS | LTA4H 1210/4885TSHR 2547/4885CA4 4250/4885 |
| US-20100173871-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CD14, DUSP3, IRAK3 | LTA4H 1363/4885TSHR 4090/4885CA4 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.