Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596652 | 0.82 | CHRM2 (0.54) | GSK3BSLC6A2SLC6A4SLC6A3HDAC3 | |
| SCHEMBL9323588 | 0.80 | PGR (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1964826 | 0.77 | GSK3B (0.61) | GSK3BTPMTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27749830 | 0.77 | HDAC3 (0.37) | SLC6A2SLC6A4SLC6A3HDAC3HDAC4 | |
| SCHEMBL9780540 | 0.77 | GSK3B (0.56) | GSK3BSLC6A4LMNA | |
| SCHEMBL5757857 | 0.74 | GSK3B (0.69) | GSK3BTPMTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11833111 | 0.72 | TDP1 (0.41) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL23714005 | 0.71 | SLC6A2 (0.45) | GSK3BSLC6A2SLC6A4SLC6A3HDAC3 | |
| SCHEMBL10863659 | 0.70 | GAA (0.46) | GSK3BSLC6A2SLC6A4SLC6A3CA1 | |
| SCHEMBL24221611 | 0.70 | LMNA (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858351-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS | LTT Bio-Pharma Co., Ltd. (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-20210198199-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS | LTT BIO-PHARMA CO., LTD. (JP) | 2021-07-01 | — | — | US | disclosed |
| WO-2020067333-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS | 株式会社ＬＴＴバイオファーマ | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198199-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS | CFTR, CCL11, MMP1 | GSK3B 1194/4885TPMT 4294/4885SLC6A2 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.