Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089108 | 0.82 | L3MBTL1 (0.54) | SLC6A2SLC6A4SLC6A3HDAC1HDAC2 | |
| SCHEMBL19305014 | 0.75 | PGR (0.47) | SLC6A2SLC6A3HDAC1HDAC2HDAC3 | |
| SCHEMBL13517660 | 0.73 | ALDH1A1 (0.40) | SLC6A2SLC6A3HDAC1HDAC2HDAC3 | |
| SCHEMBL15283012 | 0.71 | TSHR (0.42) | GAA | |
| SCHEMBL18782285 | 0.71 | L3MBTL1 (0.63) | FOLH1SMN1; SMN2 | |
| SCHEMBL21894546 | 0.71 | GSK3B (0.52) | SLC6A2SLC6A4SLC6A3GSK3BFOLH1 | |
| SCHEMBL18627182 | 0.68 | LMNA (0.51) | SLC6A3HDAC1HDAC2GAAHDAC3 | |
| SCHEMBL1964826 | 0.67 | GSK3B (0.61) | SLC6A2SLC6A4SLC6A3GSK3BGAA | |
| SCHEMBL19022029 | 0.67 | L3MBTL1 (0.71) | FOLH1SMN1; SMN2 | |
| SCHEMBL8914361 | 0.67 | NAAA (0.54) | HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858351-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS | LTT Bio-Pharma Co., Ltd. (JP) | 2021-08-04 | — | — | EP | disclosed |