SCHEMBL21896028

SCHEMBL21896028

O=C(c1ccccc1)C1CC2CCC1C2

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
HPGD P15428 3/20 0.55
KDM4E B2RXH2 2/20 0.49
HTT P42858 1/20 0.49
SLC6A3 Q01959 1/20 0.47
HSD17B10 Q99714 1/20 0.44
GRM5 P41594 2/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22570568 0.80 MCL1 (0.52) L3MBTL1HTTHSD17B10POLB
SCHEMBL7850490 0.76 KMO (0.48) L3MBTL1HTTHSD17B10POLB
SCHEMBL7850492 0.76 KMO (0.48) L3MBTL1HTTHSD17B10POLB
SCHEMBL17988308 0.76 MEN1 (0.55) L3MBTL1HPGDKDM4EHTTSLC6A3
SCHEMBL13841334 0.76 L3MBTL1 (0.56) L3MBTL1HPGDKDM4EHTTSLC6A3
SCHEMBL6454605 0.76 ALDH1A1 (0.45) MEN1KMT2A
SCHEMBL32688895 0.74 ALDH1A1 (0.47) L3MBTL1HPGDKDM4EHTTSLC6A3
SCHEMBL9920449 0.72 MCL1 (0.58) HTTNPC1RAB9A
SCHEMBL18629176 0.72 POLB (0.55) L3MBTL1HPGDKDM4EHTTHSD17B10
SCHEMBL15057174 0.72 POLB (0.55) L3MBTL1HPGDKDM4EHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SI, SIK1, CA1 L3MBTL1 2243/4885HPGD 893/4885KDM4E 3666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.