SCHEMBL21899731

SCHEMBL21899731

O=C(O)CCCOC(=O)OCCCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
SLC22A6 Q4U2R8 2/20 0.53
TSHR P16473 5/20 0.50
NFKB1 P19838 2/20 0.50
PMP22 Q01453 1/20 0.50
ALDH1A1 P00352 2/20 0.46
CAMK2A Q9UQM7 1/20 0.46
GABRR3 A8MPY1 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
HDAC3 O15379 1/20 0.43
GABBR2 O75899 1/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRR2 P28476 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18668831 0.89 ALDH1A1 (0.56) LMNASLC22A6TSHRALDH1A1KMT2A
SCHEMBL21611813 0.89 LMNA (0.42) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL26695997 0.89 LMNA (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL13911952 0.89 LMNA (0.42) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL26696160 0.89 GPR84 (0.56) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL10576578 0.85 TSHR (0.52) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL7606415 0.83 LMNA (0.53) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL18668807 0.83 ALDH1A1 (0.39) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL22206209 0.83 ALDH1A1 (0.39) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL9265748 0.83 LMNA (0.37) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1761453-A Controlled release-drug delivery system for oral administration KOREA RES INST CHEM TECH (KR) 2006-04-19 CN claimed
US-20230382881-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230382881-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230382851-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230382851-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230382880-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230382880-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-11-30 US disclosed
US-20230338543-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-10-26 US disclosed
US-20230338543-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2023-10-26 US disclosed
EP-3645413-A1 BIODEGRADABLE PACKAGING, METHOD FOR MANUFACTURING SAME AND USES THEREOF Vegeplast (FR) 2020-05-06 EP disclosed
CN-1761453-A Controlled release-drug delivery system for oral administration KOREA RES INST CHEM TECH (KR) 2006-04-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382881-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM HSD17B10, HSD17B12, HSD17B14 LMNA 2600/4885SLC22A6 952/4885TSHR 2181/4885
US-20230382880-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM HSD17B10, HSD17B12, HSD17B14 LMNA 2600/4885SLC22A6 952/4885TSHR 2181/4885
US-20230338543-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM HSD17B10, HSD17B12, HSD17B14 LMNA 2652/4885SLC22A6 1003/4885TSHR 2666/4885
US-20230382851-A1 GAMMA-HYDROXYBUTYRATE DELIVERING COMPOUNDS AND PROCESSES FOR MAKING AND USING THEM HSD17B10, HSD17B12, HSD17B14 LMNA 2600/4885SLC22A6 952/4885TSHR 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.