SCHEMBL2190244

SCHEMBL2190244

C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)c1c2ccccc2cc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.39
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37
GLA P06280 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMPD2 O60906 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2190242 1.00 AKR1B1 (0.39) AKR1B1KDM4EALDH1A1GLAHPGD
SCHEMBL1432658 0.82 SMPD2 (0.41) AKR1B1KDM4EALDH1A1MEN1KMT2A
SCHEMBL7229620 0.82 SMPD2 (0.41) AKR1B1KDM4EALDH1A1MEN1KMT2A
SCHEMBL1326634 0.82 SMPD2 (0.41) AKR1B1KDM4EALDH1A1MEN1KMT2A
SCHEMBL995191 0.79 MEN1 (0.43) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL1325516 0.79 MEN1 (0.43) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL1325515 0.79 MEN1 (0.43) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL642839 0.79 SMN1; SMN2 (0.41) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL9382586 0.79 SMN1; SMN2 (0.41) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL9057937 0.77 MMP13 (0.40) CYP1A2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277890-A1 ANTIMICROBIAL ARTICLES COMPRISING POLYURETHANE AMICOAT AS (NO) 2024-08-22 US disclosed
EP-4355097-A1 ANTIMICROBIAL ARTICLES COMPRISING POLYURETHANE Amicoat AS (NO) 2024-04-24 EP disclosed
CN-117750882-A Antimicrobial articles comprising polyurethane 埃米考特公司 2024-03-22 CN disclosed
US-20230338609-A1 MEDICAL DEVICES AND MATERIALS COMPRISING BIODEGRADABLE POLYESTERS AMICOAT AS (NO) 2023-10-26 US disclosed
US-20230233736-A1 ANTIMICROBIAL FORMULATIONS COMPRISING SILICONE AMICOAT AS (NO) 2023-07-27 US disclosed
CN-115996637-A Antimicrobial formulations comprising silicone 埃米考特公司 2023-04-21 CN disclosed
EP-4164384-A1 MEDICAL DEVICES AND MATERIALS COMPRISING BIODEGRADABLE POLYESTERS Amicoat AS (NO) 2023-04-19 EP disclosed
EP-4164385-A1 ANTIMICROBIAL FORMULATIONS COMPRISING SILICONE Amicoat AS (NO) 2023-04-19 EP disclosed
CN-115867137-A Medical devices and materials comprising biodegradable polyesters 埃米考特公司 2023-03-28 CN disclosed
WO-2022263475-A1 ANTIMICROBIAL ARTICLES COMPRISING POLYURETHANE AMICOAT AS (NO) 2022-12-22 WO disclosed
WO-2021250283-A1 MEDICAL DEVICES AND MATERIALS COMPRISING BIODEGRADABLE POLYESTERS AMICOAT AS (NO) 2021-12-16 WO disclosed
WO-2021250286-A1 ANTIMICROBIAL FORMULATIONS COMPRISING SILICONE AMICOAT AS (NO) 2021-12-16 WO disclosed
EP-2235041-B1 ANTIMICROBIAL COMPOUNDS LYTIX BIOPHARMA AS (NO) 2014-03-05 EP disclosed
US-8598114-B2 Antimicrobial compounds LYTIX BIOPHARMA AS (NO) 2013-12-03 US disclosed
US-20110172145-A1 ANTIMICROBIAL COMPOUNDS LYTIX BIOPHARMA AS (NO) 2011-07-14 US disclosed
EP-2235041-A2 ANTIMICROBIAL COMPOUNDS Lytix Biopharma AS (NO) 2010-10-06 EP disclosed
WO-2009081152-A2 ANTIMICROBIAL COMPOUNDS LYTIX BIOPHARMA AS (NO) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338609-A1 MEDICAL DEVICES AND MATERIALS COMPRISING BIODEGRADABLE POLYESTERS AGXT, ECPAS, MLX AKR1B1 776/4885KDM4E 425/4885ALDH1A1 1353/4885
US-20230233736-A1 ANTIMICROBIAL FORMULATIONS COMPRISING SILICONE CUTA, NACA, CYP4X1 AKR1B1 409/4885KDM4E 1391/4885ALDH1A1 1843/4885
US-20110172145-A1 ANTIMICROBIAL COMPOUNDS ZYX, DAO, SLC43A1 AKR1B1 400/4885KDM4E 2978/4885ALDH1A1 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.