Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962053 | 0.86 | HTR6 (0.51) | HTR6SETD7EHMT2HSD11B1ASH1L | |
| SCHEMBL2196465 | 0.80 | SETD7 (0.51) | HTR6SETD7EHMT2TSHRHSD11B1 | |
| SCHEMBL19942852 | 0.80 | HTR6 (0.45) | HTR6SETD7EHMT2HSD11B1ASH1L | |
| SCHEMBL2194262 | 0.79 | SETD7 (0.48) | HTR6SETD7EHMT2TSHRHSD11B1 | |
| SCHEMBL2193408 | 0.79 | FGFR1 (0.49) | HTR6SETD7EHMT2HSD11B1ASH1L | |
| SCHEMBL6847772 | 0.77 | DYRK1A (0.47) | HTR6MAPTTSHRHSD11B1DHODH | |
| SCHEMBL17366403 | 0.74 | HTR6 (0.42) | HTR6MAPTSETD7EHMT2HSD11B1 | |
| SCHEMBL19867977 | 0.73 | SETD7 (0.47) | HTR6MAPTSETD7EHMT2TSHR | |
| SCHEMBL6846191 | 0.72 | DHPS (0.50) | HTR6MAPTHSD11B1GSK3BMAPK14 | |
| SCHEMBL22007114 | 0.72 | SETD7 (0.39) | HTR6SETD7EHMT2HSD11B1ASH1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |