Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196465 | 0.88 | SETD7 (0.51) | SETD7EHMT2HTR6HSD11B1ASH1L | |
| SCHEMBL7962053 | 0.82 | HTR6 (0.51) | SETD7EHMT2HTR6HSD11B1ASH1L | |
| SCHEMBL2190366 | 0.79 | HTR6 (0.43) | SETD7EHMT2HTR6HSD11B1ASH1L | |
| SCHEMBL19942852 | 0.76 | HTR6 (0.45) | SETD7EHMT2HTR6HSD11B1ASH1L | |
| SCHEMBL2192864 | 0.76 | SETD7 (0.68) | SETD7EHMT2F2F10PRSS1 | |
| SCHEMBL2191641 | 0.76 | SETD7 (0.58) | SETD7EHMT2DHODHCCR2HSD17B10 | |
| SCHEMBL2193408 | 0.76 | FGFR1 (0.49) | SETD7EHMT2HTR6HSD11B1ASH1L | |
| SCHEMBL2196761 | 0.75 | SETD7 (0.81) | SETD7EHMT2ALDH1A1F2F10 | |
| SCHEMBL2193530 | 0.75 | SETD7 (0.48) | SETD7EHMT2HTR6DHODHCCR2 | |
| SCHEMBL2192071 | 0.74 | SETD7 (0.56) | SETD7EHMT2ASH1LALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |