Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19942852 | 0.93 | HTR6 (0.45) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL17366403 | 0.87 | HTR6 (0.42) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL6847772 | 0.86 | DYRK1A (0.47) | HTR6HSD11B1MAPK14HSD17B10DYRK1A | |
| SCHEMBL19867977 | 0.86 | SETD7 (0.47) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL2190366 | 0.86 | HTR6 (0.43) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL6846191 | 0.85 | DHPS (0.50) | HTR6HSD11B1MAPK14DYRK1AL3MBTL1 | |
| SCHEMBL2196465 | 0.83 | SETD7 (0.51) | HTR6HSD11B1SETD7EHMT2HSD17B10 | |
| SCHEMBL2194262 | 0.82 | SETD7 (0.48) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL2193408 | 0.82 | FGFR1 (0.49) | HTR6HSD11B1SETD7EHMT2MAPK14 | |
| SCHEMBL22007114 | 0.81 | SETD7 (0.39) | HTR6HSD11B1SETD7EHMT2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297270-B1 | HERBICIDE; DYES INTERMEDIATE, AMINO ACIDS, PHOTOSENSITIVE AND/OR THERMOSENSITIVE MATERIAL; COSMETICS; ANTIOXIDANT; ANGIOTENSIN(II) ANTAGONIST; CALCIUM CHANNEL BLOCKER, ENZYME INHIBITOR; POLYMERIZATION CATALYST | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-10-02 | — | — | US | disclosed |
| EP-1004579-A1 | Process for the preparation of 2,3-Dihydroindoles (Indolines), certain 2,3-Dihydroindoles and their use | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-05-31 | — | — | EP | disclosed |