SCHEMBL2190928

SCHEMBL2190928

COC1CC(NC(=O)OCc2ccccc2)C([N+](=O)[O-])CC1OC

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.55
ALDH1A1 P00352 2/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 2/20 0.43
TACR1 P25103 2/20 0.42
TLR4 O00206 1/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
ACHE P22303 2/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4574419 0.85 CPB1 (0.63) CPB1ALDH1A1GAATSHRCYP2C9
SCHEMBL2187150 0.79 EPHX1 (0.52) CPB1ALDH1A1GAATSHRTLR4
SCHEMBL31470357 0.76 CPB1 (0.57) CPB1ALDH1A1GAATSHRTACR1
SCHEMBL28914414 0.76 CPB1 (0.58) CPB1ALDH1A1GAATSHRCTSL
SCHEMBL20749075 0.76 CPB1 (0.58) CPB1ALDH1A1GAATSHRCTSL
SCHEMBL19630135 0.76 CPB1 (0.58) CPB1ALDH1A1GAATSHRCTSL
SCHEMBL28914412 0.76 CPB1 (0.58) CPB1ALDH1A1GAATSHRCTSL
SCHEMBL7501170 0.75 CPB1 (0.54) CPB1ALDH1A1GAATSHRCYP3A4
SCHEMBL6758772 0.75 ALDH1A1 (0.52) CPB1ALDH1A1GAATSHRTLR4
SCHEMBL23089809 0.74 CPB1 (0.90) CPB1ALDH1A1GAATSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110172421-A1 N-(alpha-AROMATIC GROUP-SUBSTITUTED-2-NITRO-4,5-DIALKOXYBENZYLOXYCARBONYL)AMINE COMPOUND AND PROCESS FOR PRODUCING THE SAME SHOWA DENKO K.K. (JP) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172421-A1 N-(alpha-AROMATIC GROUP-SUBSTITUTED-2-NITRO-4,5-DIALKOXYBENZYLOXYCARBONYL)AMINE COMPOUND AND PROCESS FOR PRODUCING THE SAME NME2, DAO, NMBR CPB1 2572/4885ALDH1A1 982/4885GAA 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.