Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376812 | 0.90 | ALDH1A1 (0.60) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21376606 | 0.85 | NR2F2 (0.48) | RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21909802 | 0.81 | MEN1 (0.53) | MAPTTNFNOD2NOD1RAB9A | |
| SCHEMBL7354099 | 0.81 | ALDH1A1 (0.80) | MAPTRAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL21376818 | 0.79 | LMNA (0.43) | KMT2ATP53MEN1 | |
| SCHEMBL665117 | 0.79 | MAPT (0.75) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL21376929 | 0.78 | MAPT (0.60) | MAPTTNFNOD2NOD1RAB9A | |
| SCHEMBL21376338 | 0.76 | SCD (0.61) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21910102 | 0.76 | NR0B1 (0.51) | RAB9ANPC1PKM | |
| SCHEMBL21909792 | 0.75 | NAMPT (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |