Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376606 | 0.82 | NR2F2 (0.48) | MEN1KMT2ARAB9APOLBSMN1; SMN2 | |
| SCHEMBL21909798 | 0.81 | MAPT (0.58) | MEN1KMT2ARAB9ATNFNOD2 | |
| SCHEMBL21909792 | 0.80 | NAMPT (0.54) | TDP1RORC | |
| SCHEMBL29979265 | 0.78 | MAPT (0.80) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL10187026 | 0.78 | MAPT (0.80) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL21376812 | 0.77 | ALDH1A1 (0.60) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL21376808 | 0.76 | RAB9A (0.54) | MEN1KMT2ARAB9ATNFNOD2 | |
| SCHEMBL21376333 | 0.75 | NPC1 (0.57) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL21910769 | 0.75 | POLB (0.39) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL21376818 | 0.74 | LMNA (0.43) | MEN1KMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |