Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665158 | 0.80 | RORC (0.61) | KDM4ERORCNPSR1TDP1 | |
| SCHEMBL21909802 | 0.80 | MEN1 (0.53) | RORCTDP1 | |
| SCHEMBL21376606 | 0.79 | NR2F2 (0.48) | NAMPTKDM4E | |
| SCHEMBL21910102 | 0.78 | NR0B1 (0.51) | — | |
| SCHEMBL21376333 | 0.78 | NPC1 (0.57) | KDM4ETDP1 | |
| SCHEMBL21909798 | 0.75 | MAPT (0.58) | — | |
| SCHEMBL21376812 | 0.75 | ALDH1A1 (0.60) | — | |
| SCHEMBL21910769 | 0.75 | POLB (0.39) | KDM4ERORCNPSR1TDP1 | |
| SCHEMBL21376536 | 0.73 | SMN1; SMN2 (0.63) | NAMPTKDM4E | |
| SCHEMBL21909747 | 0.73 | NPC1 (0.57) | KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |