Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 7/20 | 0.36 |
| ▸ | MMP13 | P45452 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25571680 | 0.92 | MAPT (0.53) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL23446186 | 0.80 | L3MBTL1 (0.40) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL28124654 | 0.74 | KDM4E (0.55) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24004174 | 0.74 | KDM4E (0.54) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3875263 | 0.73 | ALDH1A1 (0.49) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL20982288 | 0.73 | ALDH1A1 (0.40) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL24084080 | 0.73 | MAPT (0.42) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL19450424 | 0.72 | TGM2 (0.42) | MAPTALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL21698302 | 0.71 | GPR3 (0.54) | MAPTDHODHALDH1A1RAB9AHPGD | |
| SCHEMBL20425941 | 0.71 | ALDH1A1 (0.46) | MAPTDHODHALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |