SCHEMBL2191872

SCHEMBL2191872

CC1(C)NC(C)(C)c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.41
PDK4 Q16654 1/20 0.41
HTR5A P47898 2/20 0.37
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14392692 0.86 PDK2 (0.39) PDK2PDK4
SCHEMBL5594716 0.76 RAD52 (0.45)
SCHEMBL12379862 0.73 PDK2 (0.35) PDK2
SCHEMBL15679423 0.71 THRB (0.37) HTR5A
SCHEMBL24338265 0.69 PDK2 (0.40) PDK2PDK4HTR5AHTR2A
SCHEMBL29392540 0.69 HTR2A (0.48) PDK2PDK4HTR5AHTR2A
SCHEMBL29533669 0.69 PDK2 (0.40) PDK2PDK4HTR5AHTR2A
SCHEMBL1627657 0.69 HTR2A (0.48) PDK2PDK4HTR5AHTR2A
SCHEMBL28880724 0.69 PDK2 (0.40) PDK2PDK4HTR5AHTR2A
SCHEMBL22010250 0.69 PDK2 (0.46) PDK2PDK4HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140807-B1 METHOD FOR PREPARING NITROXIDES ATOFINA (FR) 2004-02-25 EP claimed
US-6538141-B1 Oxidizing secondary amine with aliphatic peracid ATOFINA (FR) 2003-03-25 US claimed
EP-0845458-B1 1,2-Bis-adducts of stable nitroxides with substituted enthylenes and stabilized compositions CIBA SC HOLDING AG (CH) 2001-11-07 EP claimed
US-6218536-B1 EFFECTIVE INHIBITORS TO PREVENT THE PREMATURE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS WHEN SUCH MONOMERS ARE DISTILLED, PROCESSED OR STORED. CIBA SPECIALTY CHEMCIALS CORPORATION 2001-04-17 US claimed
US-5844025-A 1,2-Bis-adducts of stable nitroxides with substituted ethylenes and stabilized compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-01 US claimed
EP-0845458-A1 1,2-Bis-adducts of stable nitroxides with substituted enthylenes and stabilized compositions Ciba SC Holding AG (CH) 1998-06-03 EP claimed
EP-0488403-B1 Process for the preparation of nitroxyl radicals of sterically hindered amines GREAT LAKES CHEMICAL ITALIA (IT) 1995-10-25 EP claimed
US-5218116-A Catalytic peroxidation using titanium silicalite catalyst ENICHEM SYNTHESIS S.P.A. (IT) 1993-06-08 US claimed
US-20260049097-A1 LOW DIELECTRIC COMPOUND, MANUFACTURING METHOD THEREOF, RESIN COMPOSITION, AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MATERIAL (ZHONGSHAN) CO., LTD. (CN) 2026-02-19 US disclosed
US-20250333580-A1 RESIN COMPOSITION AND PRODUCTS THEREOF ELITE ELECTRONIC MAT ZHONGSHAN CO LTD (CN) 2025-10-30 US disclosed
US-12403451-B2 Surface grafted high internal phase emulsion foams for chemical separations UNIVERSITY OF SOUTH CAROLINA (US) 2025-09-02 US disclosed
US-20250136805-A1 COPOLYMER, METHOD OF PREPARING THE SAME, RESIN COMPOSITION, AND PRODUCT OF THE SAME ELITE ELECTRONIC MATERIAL (ZHONGSHAN) CO., LTD. (CN) 2025-05-01 US disclosed
US-20240117121-A1 MULTIFUNCTIONAL NITROXIDE-MEDIATED POLYMERIZATION INITIATORS AND MULTI-ARMED POLYMERS AND HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-04-11 US disclosed
US-11820868-B2 Multifunctional nitroxide-mediated polymerization initiators and multi-armed polymers and hydrogels formed therefrom BOSTON SCIENTIFIC SCIMED, INC. (US) 2023-11-21 US disclosed
CN-1291997-A Polymers and Curable Compositions KANEKA CORP (JP) 2001-04-18 CN disclosed
US-6218536-B1 EFFECTIVE INHIBITORS TO PREVENT THE PREMATURE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS WHEN SUCH MONOMERS ARE DISTILLED, PROCESSED OR STORED. CIBA SPECIALTY CHEMCIALS CORPORATION 2001-04-17 US disclosed
CN-1265116-A Polymers and process for producing polymers KANAEKA CHEMICAL IND CORP (JP) 2000-08-30 CN disclosed
US-5844025-A 1,2-Bis-adducts of stable nitroxides with substituted ethylenes and stabilized compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-01 US disclosed
EP-0845458-A1 1,2-Bis-adducts of stable nitroxides with substituted enthylenes and stabilized compositions Ciba SC Holding AG (CH) 1998-06-03 EP disclosed
EP-0488403-B1 Process for the preparation of nitroxyl radicals of sterically hindered amines GREAT LAKES CHEMICAL ITALIA (IT) 1995-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049097-A1 LOW DIELECTRIC COMPOUND, MANUFACTURING METHOD THEREOF, RESIN COMPOSITION, AND ARTICLE MADE THEREFROM GJB2, GJA1, CDH1 PDK2 2431/4885PDK4 3180/4885HTR5A 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.