Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27094510 | 0.78 | P2RX7 (0.33) | — | |
| SCHEMBL31669380 | 0.77 | GSK3B (0.33) | GSK3B | |
| SCHEMBL8141122 | 0.74 | F12 (0.36) | GSK3B | |
| Quinoline SCHEMBL7484035 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18259028 | 0.74 | KDM1A (0.34) | GSK3BCHRNB2CHRNA4HTR1ASLC6A2 | |
| SCHEMBL19153952 | 0.74 | GSK3B (0.40) | GSK3BCHRNB2CHRNA4 | |
| SCHEMBL6332268 | 0.74 | BCHE (0.44) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29142416 | 0.73 | P2RX7 (0.31) | L3MBTL1 | |
| SCHEMBL14893181 | 0.72 | OPRL1 (0.40) | FNTAFNTBCXCR4 | |
| SCHEMBL30031899 | 0.72 | ACACB (0.43) | FNTAFNTBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063760-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2020-04-02 | — | — | WO | disclosed |