Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142426 | 0.78 | KDM4C (0.37) | P2RX7KMT2APOLBMEN1HTT | |
| SCHEMBL27094510 | 0.74 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL21920702 | 0.73 | FNTA (0.33) | L3MBTL1 | |
| SCHEMBL30031899 | 0.72 | ACACB (0.43) | L3MBTL1KDM4E | |
| SCHEMBL8141122 | 0.68 | F12 (0.36) | P2RX7KDM4E | |
| SCHEMBL34463425 | 0.66 | GSK3B (0.34) | TDP1KMT2APOLBMEN1KDM4E | |
| SCHEMBL31669380 | 0.65 | GSK3B (0.33) | P2RX7 | |
| SCHEMBL19153952 | 0.65 | GSK3B (0.40) | — | |
| SCHEMBL16292529 | 0.64 | ALOX5 (0.39) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL927784 | 0.64 | GABRA5 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177977-A | Bicyclic pyridine derivatives | 住友制药株式会社 | 2023-12-05 | — | — | CN | disclosed |