Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728790 | 0.87 | HRH3 (0.35) | HRH3LTA4H | |
| SCHEMBL507036 | 0.83 | ALDH1A1 (0.43) | MAOB | |
| SCHEMBL22604312 | 0.79 | NCF1 (0.41) | HRH3LTA4H | |
| SCHEMBL15901127 | 0.76 | CHRNB2 (0.39) | MCHR1MAOBACACB | |
| SCHEMBL11411633 | 0.74 | MAOB (0.40) | HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13736278 | 0.74 | LNPEP (0.43) | MCHR1MAOBHTR2A | |
| SCHEMBL16853366 | 0.74 | ST14 (0.40) | HRH3LTA4H | |
| SCHEMBL507305 | 0.72 | MBOAT4 (0.37) | MAOB | |
| SCHEMBL15350553 | 0.71 | P4HTM (0.55) | ACACB | |
| SCHEMBL507873 | 0.71 | MBOAT4 (0.34) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |