SCHEMBL21929031

SCHEMBL21929031

N#Cc1ccc(-c2cc(-n3c4ccc(-c5ccc(C#N)cc5C#N)cc4c4cc(-c5ccc(C#N)cc5C#N)ccc43)ncc2-n2c3ccc(-c4ccc(C#N)cc4C#N)cc3c3cc(-c4ccc(C#N)cc4C#N)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.38
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
CYP11B2 P19099 6/20 0.32
CYP11B1 P15538 1/20 0.32
ALOX5AP P20292 2/20 0.31
FEN1 P39748 2/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KIT P10721 1/20 0.31
MAP4K4 O95819 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21929275 0.95 STS (0.37) STSPRMT5WDR77ALOX5APFEN1
SCHEMBL21929214 0.93 MAP4K4 (0.36) STSPRMT5WDR77ALDH1A1KIT
SCHEMBL21929027 0.91 STS (0.38) STSPRMT5WDR77CYP11B2CYP11B1
SCHEMBL21929318 0.90 ALOX5AP (0.40) ALOX5APFEN1KDM4EALDH1A1MEN1
SCHEMBL21928412 0.90 CYP1A2 (0.40) ALOX5APFEN1KDM4EALDH1A1MEN1
SCHEMBL21929262 0.90 CYP11B2 (0.37) CYP11B2CYP11B1KDM4EALDH1A1L3MBTL1
SCHEMBL21929161 0.89 GRM5 (0.34) STSKITMAP4K4CYP1A2CYP3A4
SCHEMBL21929276 0.89 STS (0.37) STSPRMT5WDR77CYP11B2CYP11B1
SCHEMBL21929274 0.88 MAP4K4 (0.39) CYP11B2CYP11B1KDM4EALDH1A1L3MBTL1
SCHEMBL21928607 0.87 TRPA1 (0.38) ALOX5APFEN1KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388960-A1 ORGANIC MOLECULES FOR USE IN LIGHT-EMITTING DEVICES CYNORA GMBH (DE) 2022-12-08 US disclosed
EP-3609978-B1 ORGANIC MOLECULES IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-03-17 EP disclosed
US-20200136054-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200136054-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OGFR, OR51E2 STS 1151/4885PRMT5 857/4885WDR77 4668/4885
US-20220388960-A1 ORGANIC MOLECULES FOR USE IN LIGHT-EMITTING DEVICES ALDH1A2, AOX1, CYBA STS 2804/4885PRMT5 2733/4885WDR77 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.