Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172461 | 0.84 | HDAC1 (0.57) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 | |
| SCHEMBL10362477 | 0.82 | HDAC1 (0.77) | HDAC1HDAC8CYP1A2HCAR2 | |
| SCHEMBL5236795 | 0.82 | CYP1A2 (0.68) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 | |
| SCHEMBL6169879 | 0.80 | ALDH1A1 (0.60) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 | |
| SCHEMBL7450980 | 0.80 | ALDH1A1 (0.69) | HDAC1HDAC8CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9404005 | 0.78 | CYP1A2 (0.62) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 | |
| SCHEMBL7332873 | 0.78 | CYP1A2 (0.66) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 | |
| SCHEMBL5348242 | 0.78 | CYP1A2 (0.57) | HDAC1HDAC8CYP1A2CYP3A4PDPK1 | |
| SCHEMBL761158 | 0.78 | KDM4E (0.61) | CYP1A2HIF1AALDH1A1KDM4ELMNA | |
| SCHEMBL14401270 | 0.77 | PDPK1 (0.47) | HDAC1HDAC8CYP1A2HCAR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149066-B2 | Thrombospondin 1-binding peptide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149066-B2 | Thrombospondin 1-binding peptide | SERPINC1, TEK, ARGLU1 | HDAC1 1860/4885HDAC8 2591/4885CYP1A2 4728/4885 |
| US-20200131230-A1 | THROMBOSPONDIN 1-BINDING PEPTIDE | SERPINC1, TEK, ARGLU1 | HDAC1 1860/4885HDAC8 2591/4885CYP1A2 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.