Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935727 | 0.72 | PORCN (0.58) | — | |
| SCHEMBL10114484 | 0.71 | TP53 (1.00) | TP53POLBMAPK1RXFP1 | |
| SCHEMBL4518207 | 0.70 | TSHR (0.38) | MAPTPOLBALDH1A1HTT | |
| SCHEMBL21936455 | 0.70 | PORCN (0.51) | MAPT | |
| SCHEMBL11173152 | 0.69 | DRD4 (0.53) | TP53MAPTPOLBMAPK1DRD4 | |
| SCHEMBL4532619 | 0.68 | ALDH1A1 (0.41) | MAPTPOLBALDH1A1 | |
| SCHEMBL20079704 | 0.68 | TRPA1 (0.37) | TP53MAPTPOLBMAPK1RXFP1 | |
| SCHEMBL12923166 | 0.67 | POLB (0.64) | MAPTPOLBMAPK1ALDH1A1HTT | |
| SCHEMBL12812272 | 0.65 | POLB (0.65) | MAPTPOLBALDH1A1HTT | |
| SCHEMBL11414687 | 0.65 | POLB (0.61) | MAPTPOLBMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELI LILLY AND COMPANY | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194202-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | TP53 1505/4885MAPT 2844/4885POLB 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.