Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437314 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL482181 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL12419165 | 0.76 | RIPK1 (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL14723767 | 0.75 | CYP2C19 (0.38) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL6081630 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL12513926 | 0.74 | MEN1 (0.59) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2735484 | 0.73 | EPHX1 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL13346829 | 0.73 | RIPK1 (0.41) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| Anthracene-9-Carboxylic Acid SCHEMBL28344339 | 0.73 | KDM4E (0.81) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2735485 | 0.72 | ADRB2 (0.45) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | ALDH1A1 2016/4885HPGD 1518/4885MEN1 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.