Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221437 | 0.85 | POLB (0.46) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL31753526 | 0.85 | POLB (0.46) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL15841353 | 0.83 | POLB (0.44) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL10621993 | 0.75 | — | — | |
| SCHEMBL21761728 | 0.73 | POLB (0.39) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL18360210 | 0.72 | — | — | |
| SCHEMBL8209943 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL29448462 | 0.71 | POLB (0.40) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL11408342 | 0.69 | — | — | |
| SCHEMBL11408346 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200113937-A1 | TARGETED IONOPHORE-BASED METAL DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113937-A1 | TARGETED IONOPHORE-BASED METAL DELIVERY | SLC8B1, SLC47A2, ATP2A2 | KMT2A 3679/4885MEN1 1322/4885NPSR1 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.