SCHEMBL29448462

SCHEMBL29448462

CNC(=S)N/N=C\C=O.CNC(=S)N/N=C\C=O.[Cu]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 4/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 3/20 0.39
NPC1 O15118 2/20 0.39
GAA P10253 2/20 0.39
GLA P06280 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 2/20 0.38
TOP2A P11388 1/20 0.38
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALOX12 P18054 2/20 0.36
ALDH1A1 P00352 3/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21940521 0.98
SCHEMBL15841353 0.86 POLB (0.44) POLBHTTNPSR1KDM4EMAPT
SCHEMBL8221437 0.84 POLB (0.46) POLBHTTNPSR1KDM4EMAPT
SCHEMBL18360210 0.76
SCHEMBL21761728 0.72 POLB (0.39) POLBHTTNPSR1KDM4EMAPT
SCHEMBL11408346 0.72
SCHEMBL11408342 0.72
SCHEMBL8209943 0.71 ALDH1A1 (0.46) POLBHTTNPSR1KDM4EMAPT
SCHEMBL21940347 0.71 KMT2A (0.46) POLBHTTNPSR1KDM4EMAPT
SCHEMBL28224064 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 WO claimed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 US claimed
US-20220378913-A1 METHODS FOR DIAGNOSIS AND TREATMENT GMDX CO PTY LTD (AU) 2022-12-01 US claimed
CN-115040667-A Nuclide-iodized oil homogeneous preparation and preparation method and application thereof 厦门大学 2022-09-13 CN claimed
EP-4048814-A1 METHODS FOR DIAGNOSIS AND TREATMENT GMDx Co Pty Ltd (AU) 2022-08-31 EP claimed
US-20260144846-A1 Modulation Of Tumor Immunity By Protein-Mediated O2 Delivery OMNIOX, INC. (US) 2026-05-28 US disclosed
US-12533427-B2 Radioactive antitumor agent NATIONAL INSTITUTES FOR QUANTUM SCIENCE & TECHNOLOGY (JP) 2026-01-27 US disclosed
US-12522618-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2026-01-13 US disclosed
US-12473522-B2 Methods and systems for cell labeling and imaging CELLFE, INC. (US) 2025-11-18 US disclosed
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 WO disclosed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 US disclosed
US-20250295869-A1 ADMINISTRATION OF HYPOXIA ACTIVATED PRODRUGS AND ANTIANGIOGENIC AGENTS FOR THE TREATMENT OF CANCER THRESHOLD PHARMACEUTICALS, INC. 2025-09-25 US disclosed
CN-110585607-B System and method for use in emission guided radiation therapy 反射医疗公司 2022-07-19 CN disclosed
EP-4021454-A1 COPPER-ATSM FOR TREATING NEURODEGENERATIVE DISORDERS ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION Research Institute at Nationwide Children's Hospital (US) 2022-07-06 EP disclosed
US-20220175973-A1 METHOD FOR PRODUCING RADIOPHARMACEUTICAL AND RADIOPHARMACEUTICAL National Institutes for Quantum Science and Technology (JP) 2022-06-09 US disclosed
US-20220160823-A1 MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED O2 DELIVERY OMNIOX, INC. 2022-05-26 US disclosed
CN-112962125-B Method for preparing 64Ni target and 64Cu nuclide and application thereof 原子高科股份有限公司 2022-05-17 CN disclosed
US-20220096867-A1 SYSTEMS AND METHODS FOR USE IN EMISSION GUIDED RADIATION THERAPY OXFORD FINANCE LLC 2022-03-31 US disclosed
WO-2022064812-A1 METHOD FOR PRODUCING RADIOACTIVE LABELED SUBSTANCE, DEVICE FOR PRODUCING RADIOACTIVE LABELED SUBSTANCE, AND METHOD FOR EVAPORATING AND CONCENTRATING RADIOACTIVE METAL NUCLIDE 国立研究開発法人量子科学技術研究開発機構 2022-03-31 WO disclosed
US-11266686-B2 Metal complexes and methods of treatment PROCYPRA THERAPEUTICS LLC (US) 2022-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533427-B2 Radioactive antitumor agent IDH2, MT-CO1, ALDH2 POLB 1496/4885HTT 2193/4885NPSR1 2587/4885
US-11266686-B2 Metal complexes and methods of treatment NLN, PNMT, BDNF POLB 3985/4885HTT 230/4885NPSR1 34/4885
US-20260144846-A1 Modulation Of Tumor Immunity By Protein-Mediated O2 Delivery CD4, HIF1A, HIF1AN POLB 1059/4885HTT 2657/4885NPSR1 3868/4885
US-20220175973-A1 METHOD FOR PRODUCING RADIOPHARMACEUTICAL AND RADIOPHARMACEUTICAL CTH, MGMT, TST POLB 3451/4885HTT 1216/4885NPSR1 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.