Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867409 | 0.85 | AGTR2 (0.52) | AGTR2HSD17B3OPRM1OPRD1OPRK1 | |
| SCHEMBL4278365 | 0.81 | ACE (0.54) | ACE | |
| SCHEMBL5847071 | 0.81 | ACE (0.54) | ACE | |
| SCHEMBL5847068 | 0.81 | ACE (0.54) | ACE | |
| SCHEMBL28340121 | 0.78 | NOTUM (0.38) | HSD17B3 | |
| SCHEMBL27867498 | 0.75 | AGTR2 (0.51) | AGTR2HSD17B3OPRM1OPRD1OPRK1 | |
| SCHEMBL27883889 | 0.74 | AGTR2 (0.43) | AGTR2 | |
| Guanidine SCHEMBL8691609 | 0.73 | ACE (0.47) | ACE | |
| SCHEMBL27883822 | 0.73 | OPRD1 (0.43) | AGTR2OPRM1OPRD1OPRK1 | |
| SCHEMBL27883815 | 0.73 | MMP8 (0.43) | AGTR2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |