Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867409 | 0.89 | AGTR2 (0.52) | AGTR2UCHL1OPRM1OPRD1OPRK1 | |
| SCHEMBL27867411 | 0.88 | MMP8 (0.42) | AGTR2HSD17B3MMP8MMP3 | |
| SCHEMBL27867447 | 0.88 | OPRD1 (0.43) | AGTR2OPRM1OPRD1OPRK1MMP8 | |
| SCHEMBL27883804 | 0.88 | KMO (0.46) | AGTR2 | |
| SCHEMBL27883807 | 0.85 | AADAT (0.43) | AGTR2MMP8MMP3 | |
| SCHEMBL27883817 | 0.83 | FFAR1 (0.47) | AGTR2MMP8MMP3 | |
| SCHEMBL1445011 | 0.80 | ACE (0.51) | — | |
| SCHEMBL27883889 | 0.78 | AGTR2 (0.43) | AGTR2 | |
| SCHEMBL27867426 | 0.78 | NOTUM (0.42) | AGTR2 | |
| SCHEMBL27883816 | 0.78 | TDP2 (0.43) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | claimed |
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |