Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708819 | 0.80 | GAA (0.62) | MEN1KMT2AGAAPKMALDH1A1 | |
| SCHEMBL13302259 | 0.79 | KMT2A (0.77) | MEN1KMT2AGAAPKMALDH1A1 | |
| SCHEMBL26240915 | 0.79 | LMNA (0.65) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL611622 | 0.79 | PKM (0.58) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL10017628 | 0.75 | HSD11B1 (0.72) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL17888275 | 0.73 | ALDH1A1 (0.67) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL23564493 | 0.73 | PKM (0.53) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL12550394 | 0.69 | HSD11B1 (1.00) | HSD11B1MEN1KMT2AGAAPKM | |
| SCHEMBL11773546 | 0.69 | PKM (0.61) | MEN1KMT2AGAAPKMALDH1A1 | |
| SCHEMBL1953531 | 0.69 | HSD11B1 (0.68) | HSD11B1MEN1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636625-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ISOMER, OPTICALLY ACTIVE ISOMER, METHOD FOR PRODUCING CHIRAL MOLECULES, AND CHIRAL MOLECULES | Kyushu University, National University Corporation (JP) | 2020-04-15 | — | — | EP | disclosed |