Sugi Predict

Sugi Predict / Compounds / SCHEMBL611622

SCHEMBL611622

SCHEMBL611622

CC1=CCN(S(=O)(=O)c2ccc(C)cc2)C1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 3/20 0.58
▸ HTT P42858 2/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ LMNA P02545 3/20 0.52
▸ HSD11B1 P28845 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ KMT2A Q03164 4/20 0.51
▸ MEN1 O00255 3/20 0.51
▸ GAA P10253 2/20 0.51
▸ MMP2 P08253 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23564493 0.86 PKM (0.53) PKMHTTALDH1A1POLBLMNA
Ethoxycarbonyl Group SCHEMBL29037281 0.85 KMT2A (0.44) PKMHTTALDH1A1POLBLMNA
SCHEMBL13970050 0.83 PKM (0.59) PKMHTTALDH1A1POLBLMNA
SCHEMBL26240915 0.83 LMNA (0.65) PKMHTTALDH1A1POLBLMNA
SCHEMBL16080323 0.80 DHCR7 (0.50) PKM
SCHEMBL14838584 0.79 PKM (0.50) PKMHTTALDH1A1POLBLMNA
SCHEMBL19559858 0.79 LMNA (0.52) PKMHTTALDH1A1POLBLMNA
SCHEMBL10017628 0.79 HSD11B1 (0.72) PKMHTTALDH1A1POLBLMNA
SCHEMBL21941978 0.79 HSD11B1 (0.53) PKMHTTALDH1A1POLBLMNA
SCHEMBL21829100 0.78 PKM (0.49) PKMHTTALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) 2025-02-06 — — US disclosed
EP-4433451-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF Ecole Nationale Supérieure de Chimie de Rennes (FR) 2024-09-25 — — EP disclosed
CN-111116446-B Synthetic process method of 3-substituted-1H-pyrrole 成都师范学院 2023-07-14 — — CN disclosed
WO-2023088919-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) 2023-05-25 — — WO disclosed
CN-108654695-B Indole [3,2-a ] oxazolidine-labeled ruthenium carbene catalyst, and preparation method and application thereof 天津大学 2021-04-06 — — CN disclosed
CN-108654695-A The ruthenium carbone catalyst and preparation method and application of indoles [3,2-a] oxazolidine label 天津大学 2018-10-16 — — CN disclosed
CN-108659048-A Nitrogenous coordination ruthenium carbone catalyst and preparation method and application 天津大学 2018-10-16 — — CN disclosed
US-9988339-B2 Nonpolar phase-soluble metathesis catalysts THE TEXAS A&M UNIVERSITY SYSTEM (US) 2018-06-05 — — US disclosed
US-9527877-B2 Metal complexes, their application and methods of carrying out of metathesis reaction APEIRON SYNTHESIS S.A. (PL) 2016-12-27 — — US disclosed
US-9527877-B2 Metal complexes, their application and methods of carrying out of metathesis reaction APEIRON SYNTHESIS S.A. (PL) 2016-12-27 — — US disclosed
US-7632772-B2 Recyclable ruthenium catalysts for metathesis reactions Zhan, Zheng-Yun James (CN) 2009-12-15 — — US disclosed
US-7632772-B2 Recyclable ruthenium catalysts for metathesis reactions Zhan, Zheng-Yun James (CN) 2009-12-15 — — US disclosed
US-20090203860-A1 Nonpolar phase-soluble methathesis catalysts NATIONAL SCIENCE FOUNDATION 2009-08-13 — — US disclosed
US-20090203860-A1 Nonpolar phase-soluble methathesis catalysts NATIONAL SCIENCE FOUNDATION 2009-08-13 — — US disclosed
US-20090170692-A1 CATALYSTS FOR RING-CLOSING METATHESIS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2009-07-02 — — US disclosed
WO-2009009597-A1 WATER SOLUBLE OLEFIN METATHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-01-15 — — WO disclosed
EP-1905777-A1 RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF Zhan, Zheng-Yun (CN) 2008-04-02 — — EP disclosed
WO-2007117221-A1 CATALYSTS FOR RING CLOSING METATHESIS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2007-10-18 — — WO disclosed
US-20070043180-A1 Recyclable ruthenium catalysts for metathesis reactions ZHENG-YUN JAMES ZHAN (CN) 2007-02-22 — — US disclosed
US-20070043180-A1 Recyclable ruthenium catalysts for metathesis reactions ZHENG-YUN JAMES ZHAN (CN) 2007-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203860-A1 Nonpolar phase-soluble methathesis catalysts MMAB, HMBS, PEAK1 PKM 1039/4885HTT 14/4885ALDH1A1 3476/4885
US-20070043180-A1 Recyclable ruthenium catalysts for metathesis reactions RPIA, REV1, RCSD1 PKM 1349/4885HTT 3521/4885ALDH1A1 2069/4885
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF SQLE, SYMPK, FDFT1 PKM 4697/4885HTT 2939/4885ALDH1A1 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.