Water

Water

SCHEMBL219444

O.O.O.O.O.O.O.O.O.O=[N+]([O-])[O-].[Co]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
CA5A P35218 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2845077 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL218426 1.00
Water SCHEMBL3891351 1.00
Water SCHEMBL72145 1.00 MEN1 (0.67) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28478211 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL2590832 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL28398822 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
SCHEMBL2198408 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10896609 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR
Water SCHEMBL10566608 0.94 MEN1 (0.75) MEN1KMT2ACA5ACA5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912700-A Preparation method of hollow-morphology bimetal organic framework material 河南城建学院 2025-05-02 CN claimed
CN-116815223-B Electrode and preparation method and application thereof 有研(广东)新材料技术研究院 2025-02-07 CN claimed
CN-115483381-B Amorphous cobalt oxide/carbon/metal organic framework composite material and preparation method and application thereof 华南师范大学 2024-11-12 CN claimed
CN-118738683-A High-activity positive electrode material for lithium carbon dioxide battery 北京理工大学 2024-10-01 CN claimed
CN-115094475-B Electrode material with high-performance oxygen evolution catalytic activity and preparation method thereof 河北工业大学 2024-04-16 CN claimed
CN-117655322-A Ternary composite nano wave-absorbing material with hollow double-spherical-shell structure, and preparation method and application thereof 南京航空航天大学 2024-03-08 CN claimed
CN-117650228-A Porous lithium metal anode material based on metal organic framework modification and preparation method thereof 江西硅瀛新能源科技有限公司 2024-03-05 CN claimed
CN-116815223-A Electrode and preparation method and application thereof 有研(广东)新材料技术研究院 2023-09-29 CN claimed
CN-115483381-A Amorphous cobalt oxide/carbon/metal organic framework composite material and preparation method and application thereof 华南师范大学 2022-12-16 CN claimed
CN-115094475-A Electrode material with high-performance oxygen evolution catalytic activity and preparation method thereof 河北工业大学 2022-09-23 CN claimed
CN-113036124-A Alizarin MOF/graphene composite electrode material, and preparation method and application thereof 新乡学院 2021-06-25 CN claimed
CN-109012687-B MnO (MnO)2Preparation method and application of/CoAl-LDO (low-temperature flue gas denitration catalyst) 太原理工大学 2021-05-18 CN claimed
CN-108927170-B Preparation method and application of low-temperature flue gas denitration catalyst based on CoMnAl hydrotalcite-like compound 太原理工大学 2021-02-05 CN claimed
CN-108585044-B Co-MoO with mylikes structure2Simple preparation and electrocatalysis application of nanosphere 济南大学 2021-01-19 CN claimed
CN-119383939-B Carbon composite wave-absorbing material and preparation method thereof HEFEI UNIVERSITY OF TECHNOLOGY (CN) 2026-05-26 CN disclosed
CN-122057556-A FeCo/ZSM-5 catalyst and preparation method and application thereof 南京航空航天大学 2026-05-19 CN disclosed
CN-122068041-A Method for modifying graphite current collector through LDHs and modified graphite current collector 贵州电网有限责任公司 2026-05-19 CN disclosed
US-5811365-A CATALYST SUPPORTS; SHRINKAGE INHIBITION THE BRITISH PETROLEUM COMPANY, P.L.C. (GB) 1998-09-22 US disclosed
EP-0671976-A1 ZINC OXIDE COMPOSITION FOR USE IN CATALYSTS THE BRITISH PETROLEUM COMPANY P.L.C. (GB) 1995-09-20 EP disclosed
WO-1994013400-A1 ZINC OXIDE COMPOSITION FOR USE IN CATALYSTS THE BRITISH PETROLEUM COMPANY PLC (GB) 1994-06-23 WO disclosed