Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.47 |
| ▸ | FPR2 | P25090 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SDHB | P21912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002850 | 0.86 | MAPT (0.48) | ADORA3SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL2259750 | 0.82 | ADORA3 (0.56) | ADORA3SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL16845409 | 0.82 | SCN9A (0.54) | ADORA3MAPTSCN9AFPR2 | |
| SCHEMBL3725418 | 0.81 | SCN9A (0.57) | ADORA3CASP1SCN9AFPR2 | |
| SCHEMBL4265804 | 0.81 | ALDH1A1 (0.57) | ADORA3SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL18003400 | 0.80 | KDM4E (0.56) | SMN1; SMN2ALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL16845408 | 0.79 | SCN9A (0.58) | SCN9AFPR2 | |
| SCHEMBL15534617 | 0.78 | ADORA3 (0.50) | ADORA3SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL1549339 | 0.77 | CFTR (0.46) | ADORA3SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL3721217 | 0.77 | SCN9A (0.53) | ADORA3CASP1SCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | ADORA3 3071/4885SMN1; SMN2 3834/4885ALDH1A1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.