Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413618 | 0.88 | DRD1 (0.57) | DRD1ALDH1A3ALOX15GFERADAM17 | |
| SCHEMBL1748564 | 0.81 | ALDH1A3 (0.55) | ALDH5A1ABATBACE1PTGS2ALDH1A3 | |
| SCHEMBL24036554 | 0.79 | DRD1 (0.49) | DRD1ALDH1A3ALOX15GFERADAM17 | |
| SCHEMBL2497078 | 0.79 | DRD1 (0.49) | DRD1ALDH1A3MEN1ALDH1A1KMT2A | |
| SCHEMBL25752940 | 0.77 | DRD1 (0.46) | DRD1ALDH1A3MEN1ALDH1A1KMT2A | |
| SCHEMBL22926439 | 0.75 | ALDH1A1 (0.47) | DRD1ALOX15GFERADAM17MEN1 | |
| SCHEMBL29556004 | 0.75 | ALDH1A1 (0.47) | DRD1ALOX15GFERADAM17MEN1 | |
| SCHEMBL29177359 | 0.74 | DRD1 (0.44) | DRD1PTGS2TTRALOX15MAPK1 | |
| SCHEMBL17203921 | 0.74 | CA12 (0.50) | ALOX15GFERADAM17MAPK1NLRP3 | |
| SCHEMBL378297 | 0.74 | CYP1A1 (0.58) | ALDH5A1ABATBACE1PTGS2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | DRD1 4556/4885ALDH5A1 224/4885ABAT 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.