Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293710 | 0.83 | SMN1; SMN2 (0.58) | DRD2TDP1HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL26014815 | 0.82 | CXCR4 (0.58) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL22375323 | 0.82 | CXCR4 (0.58) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL1259602 | 0.78 | SIGMAR1 (0.71) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL21961925 | 0.78 | SIGMAR1 (0.71) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL6237364 | 0.77 | SIGMAR1 (0.61) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| Bromide SCHEMBL1259195 | 0.76 | SIGMAR1 (0.69) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL12420616 | 0.76 | SIGMAR1 (0.48) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| SCHEMBL13499190 | 0.75 | SMN1; SMN2 (0.49) | TDP1MEN1KMT2AHRH3SMN1; SMN2 | |
| SCHEMBL674945 | 0.74 | CXCR4 (0.75) | SIGMAR1CXCR4TDP1MEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | SIGMAR1 1928/4885DRD2 1917/4885CXCR4 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.