Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313673 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL25891673 | 0.76 | ALDH1A1 (0.34) | ALDH1A1TSHRMEN1KMT2ATAS1R3 | |
| SCHEMBL21949129 | 0.73 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL16958755 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2ATAS1R3 | |
| SCHEMBL26552444 | 0.72 | KDM4E (0.55) | ALDH1A1KMT2AKDM4ELMNAHPGD | |
| SCHEMBL3716770 | 0.70 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2ATAS1R3 | |
| SCHEMBL19332733 | 0.69 | MEN1 (0.32) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL19331001 | 0.69 | MEN1 (0.32) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL19332734 | 0.69 | MEN1 (0.32) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL19332730 | 0.69 | MEN1 (0.32) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |