Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949128 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2A | |
| SCHEMBL21949120 | 0.70 | GABRA1 (0.39) | — | |
| SCHEMBL25891673 | 0.67 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL28115604 | 0.67 | DRD2 (0.40) | MEN1KMT2A | |
| SCHEMBL5313673 | 0.65 | ALDH1A1 (0.60) | MEN1KMT2A | |
| SCHEMBL1132630 | 0.64 | KDM4E (0.37) | MEN1KMT2A | |
| SCHEMBL25769800 | 0.63 | DRD2 (0.42) | MEN1KMT2A | |
| SCHEMBL27018581 | 0.62 | AKR1C3 (0.43) | MEN1KMT2A | |
| SCHEMBL1707904 | 0.62 | ALDH1A1 (0.44) | KMT2A | |
| SCHEMBL4197382 | 0.62 | CYP2C9 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |