Sugi Predict

Sugi Predict / Compounds / SCHEMBL5313673

SCHEMBL5313673

SCHEMBL5313673

Cc1cccc(C=O)c1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.60
▸ TSHR P16473 1/20 0.60
▸ TDP1 Q9NUW8 3/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ LMNA P02545 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ TRIM24 O15164 2/20 0.44
▸ TRIM33 Q9UPN9 2/20 0.44
▸ ERN1 O75460 3/20 0.40
▸ TLR2 O60603 1/20 0.38
▸ TLR1 Q15399 1/20 0.38
▸ TLR6 Q9Y2C9 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CYP1A2 P05177 2/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794351 0.83 TDP1 (0.58) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL3936518 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL3716770 0.79 ALDH1A1 (0.39) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL8608699 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL16958755 0.77 ALDH1A1 (0.39) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL3686691 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL21949128 0.77 ALDH1A1 (0.39) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL95211 0.76 ALDH1A1 (0.54) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL29444 0.76 TSHR (0.65) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL30011286 0.76 ALDH1A1 (0.54) ALDH1A1TSHRTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730822-A Continuous preparation method of 2-chloro-3-methylbenzoic acid 联化科技（德州）有限公司 2023-09-12 — — CN claimed
CN-116730833-A Preparation method of 2-chloro-3-methylbenzoic acid 联化科技（德州）有限公司 2023-09-12 — — CN claimed
EP-3737680-A1 OCTAHYDROPYRIDO[1,2-ALPHA]PYRAZINES AS MAGL INHIBITORS F. Hoffmann-La Roche AG (CH) 2020-11-18 — — EP claimed
WO-2019134985-A1 OCTAHYDROPYRIDO[1,2-ALPHA]PYRAZINES AS MAGL INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2019-07-11 — — WO claimed
CN-122070275-A Heterocyclic compound and application thereof 成都麻沸散医药科技有限公司 2026-05-19 — — CN disclosed
CN-116730833-B Preparation method of 2-chloro-3-methylbenzoic acid 联化科技（德州）有限公司 2026-04-17 — — CN disclosed
US-12507586-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-12-23 — — US disclosed
WO-2024068656-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 — — WO disclosed
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE AMGEN INC. 2024-02-22 — — US disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 — — US disclosed
EP-3884939-B1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS INC (US) 2023-10-25 — — EP disclosed
US-20230312536-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-10-05 — — US disclosed
US-4268442-A REACTING AN AROMATIC ALKEHYDE WITH A TRIHALOMETHANE AND AN ALKANETHIOL IN THE PRESENCE OF A BASE AND AN APROTIC SOLVENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1981-05-19 — — US disclosed
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 — — US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 — — US disclosed
EP-0011279-A1 Process for the preparation of aromatically substituted acetic acids SAGAMI CHEMICAL RESEARCH CENTER (JP) 1980-05-28 — — EP disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 — — US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 — — US disclosed
US-4062961-A SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINES SMITHKLINE CORPORATION (US) 1977-12-13 — — US disclosed
US-3988339-A 7 OR 8-SUBSTITUTED 1,2,3,4-TETRAHYDRO-ISOQUINOLINE SMITHKLINE CORPORATION (US) 1976-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF PHGDH, G6PD, PGD ALDH1A1 222/4885TSHR 4686/4885TDP1 832/4885
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE KRAS, HRAS, APC ALDH1A1 1221/4885TSHR 4163/4885TDP1 4325/4885
US-20230312536-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF PHGDH, G6PD, PGD ALDH1A1 222/4885TSHR 4686/4885TDP1 832/4885
US-12507586-B2 Organic electroluminescent materials and devices OXER1, OXSR1, OSR1 ALDH1A1 1504/4885TSHR 250/4885TDP1 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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