Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794927 | 0.84 | KDM4E (0.54) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL10794933 | 0.84 | KDM4E (0.54) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL12173470 | 0.84 | KDM4E (0.65) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL30379656 | 0.78 | LMNA (0.48) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL20603125 | 0.78 | LMNA (0.48) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL10733520 | 0.78 | TRPA1 (0.61) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL10733517 | 0.78 | TRPA1 (0.61) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL14690024 | 0.76 | EGFR (0.50) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL14690026 | 0.76 | EGFR (0.50) | KDM4EKMT2ALMNAPKMEGFR | |
| SCHEMBL21457666 | 0.73 | EGFR (0.58) | KDM4EKMT2ALMNAPKMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | KDM4E 1615/4885KMT2A 2693/4885LMNA 3304/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | KDM4E 1615/4885KMT2A 2693/4885LMNA 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.