Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28785908 | 0.76 | KMT2A (0.57) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL19306397 | 0.73 | KMT2A (0.78) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL744601 | 0.70 | KMT2A (0.56) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL747914 | 0.70 | KMT2A (0.66) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL747775 | 0.70 | HCRTR2 (0.73) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL5161712 | 0.69 | MEN1 (0.48) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL6828413 | 0.68 | EHMT2 (0.47) | KMT2AMEN1CYP2C19EHMT2HPGD | |
| SCHEMBL23470173 | 0.67 | EHMT2 (0.55) | KMT2AMEN1POLBCYP2C9CYP2C19 | |
| SCHEMBL21538655 | 0.67 | LMNA (0.50) | KMT2AMEN1EHMT2HPGDLMNA | |
| SCHEMBL29039808 | 0.67 | EHMT2 (0.50) | KMT2AMEN1POLBCYP2C19EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123146-A1 | HETEROCYCLIC INTEGRIN AGONISTS | GB006 INC (US) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123146-A1 | HETEROCYCLIC INTEGRIN AGONISTS | ITGA1, ITGA4, ITGA2 | KMT2A 2000/4885MEN1 3711/4885POLB 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.