Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 7/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288587 | 0.82 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL3764257 | 0.80 | RAB9A (0.55) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL8493097 | 0.80 | CA12 (0.66) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL6801086 | 0.78 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL21953836 | 0.78 | CES2 (0.52) | ALDH1A1L3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL11927841 | 0.78 | RAB9A (0.54) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL12831174 | 0.77 | RAB9A (0.52) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL7397626 | 0.77 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL11228519 | 0.77 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL3316733 | 0.77 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1KMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891129-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020117525-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117525-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-06-11 | — | — | WO | disclosed |
| US-10633340-B1 | Synthesis of oxime nerve agent antidotes | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633340-B1 | Synthesis of oxime nerve agent antidotes | ACHE, BCHE, PNPO | ALDH1A1 1751/4885L3MBTL1 1758/4885KMT2A 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.