SCHEMBL219558

SCHEMBL219558

C=C(C)C(=O)OOc1ccc(O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.41
MAPT P10636 2/20 0.39
KMT2A Q03164 4/20 0.38
ATM Q13315 1/20 0.38
MEN1 O00255 3/20 0.38
ESR2 Q92731 2/20 0.38
ESR1 P03372 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LTA4H P09960 1/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PARP10 Q53GL7 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18626244 0.85 LMNA (0.48) ELANEMAPTKMT2AATMALDH1A1
SCHEMBL7098470 0.83 ELANE (0.40) ELANEMAPTKMT2AATMALDH1A1
SCHEMBL632410 0.82 ELANE (0.50) ELANEMAPTKMT2AATMALDH1A1
SCHEMBL9109314 0.81 POLB (0.55) ELANEMAPTKMT2AMEN1ALDH1A1
SCHEMBL72362 0.80 ELANE (0.61) ELANEMAPTKMT2AATMMEN1
SCHEMBL6200881 0.79 MEN1 (0.44) ELANEMAPTKMT2AMEN1ESR2
Methacrylic Acid SCHEMBL2939572 0.79 ELANE (0.47) ELANEMAPTKMT2AATMALDH1A1
SCHEMBL31634553 0.78 MAPT (0.57) ELANEMAPTKMT2AMEN1ALDH1A1
SCHEMBL28399621 0.78 ELANE (0.71) ELANEMAPTALDH1A1HTTGAA
Hydroquinone SCHEMBL27381842 0.77 ALDH1A1 (0.44) ELANEMAPTKMT2AMEN1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
CN-105900014-B Polyoxometallate and heteropolyoxometalate compositions and methods of use thereof AZ电子材料卢森堡有限公司 2019-09-03 CN disclosed
CN-103597043-B Bottom antireflective coating compositions and its method 默克专利有限公司 2017-04-05 CN disclosed
CN-105900014-A Polyoxometallate and heteropolyoxometalate compositions and methods of use thereof AZ电子材料卢森堡有限公司 2016-08-24 CN disclosed
EP-2718379-B1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF MERCK PATENT GMBH (DE) 2016-08-17 EP disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
CN-103869623-A Coating composition AZ ELECTRONIC MATERIALS USA 2014-06-18 CN disclosed
CN-102209937-B Coating composition AZ ELECTRONIC MATERIALS USA 2014-06-11 CN disclosed
EP-2718379-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ Electronic Materials USA Corp. (US) 2014-04-16 EP disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-20120122029-A1 Underlayer Developable Coating Compositions and Processes Thereof AZ ELECTRONIC MATERIALS USA CORP. 2012-05-17 US disclosed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
EP-2384457-A2 COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2011-11-09 EP disclosed
CN-102209937-A Coating composition AZ ELECTRONIC MATERIALS USA 2011-10-05 CN disclosed
CN-101835735-A Bottom antireflective coating composition AZ ELECTRONIC MATERIALS USA 2010-09-15 CN disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 ELANE 3373/4885MAPT 971/4885KMT2A 1852/4885
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 ELANE 2119/4885MAPT 488/4885KMT2A 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.