Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427427 | 0.71 | LPO (0.32) | — | |
| SCHEMBL31710606 | 0.63 | — | — | |
| SCHEMBL28955974 | 0.60 | ATAD2 (0.47) | KDM4EGAA | |
| SCHEMBL21960925 | 0.57 | MAPT (0.42) | KDM4EGAA | |
| SCHEMBL13665439 | 0.57 | — | — | |
| SCHEMBL11781503 | 0.55 | P2RX4 (0.41) | KDM4EGAA | |
| SCHEMBL19513637 | 0.54 | BRD4 (0.43) | — | |
| SCHEMBL7190777 | 0.54 | — | — | |
| SCHEMBL18658873 | 0.52 | KDM4E (0.33) | KDM4E | |
| SCHEMBL1430242 | 0.49 | MAPT (0.50) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478675-B1 | HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-22 | — | — | EP | disclosed |