SCHEMBL427427

SCHEMBL427427

CONc1cn(C)c(=S)[nH]c1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LPO P22079 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28074920 0.82 DAO (0.36) KMT2A
SCHEMBL27905995 0.80 MEN1 (0.33) MEN1KMT2A
SCHEMBL6037466 0.71 PARP1 (0.38) KMT2A
SCHEMBL12231817 0.71 RAB9A (0.34) MEN1KMT2A
SCHEMBL21960934 0.71 IKBKB (0.32) —
SCHEMBL16575964 0.68 LMNA (0.37) LPOMEN1KMT2A
SCHEMBL28313542 0.68 KMT2A (0.35) LPOMEN1KMT2A
SCHEMBL27783881 0.68 KDM3B (0.42) MEN1KMT2A
SCHEMBL28955974 0.63 ATAD2 (0.47) MEN1KMT2A
SCHEMBL2490715 0.61 DAO (0.40) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 — — US claimed
US-12638452-B2 Nanopore assemblies and uses thereof OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-26 — — US disclosed
US-20260097094-A1 METHODS FOR INHIBITING DIAZEPAM BINDING PROTEIN INST NAT SANTE RECH MED (FR) 2026-04-09 — — US disclosed
US-12539510-B2 Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge CEPHEID (US) 2026-02-03 — — US disclosed
US-12517124-B2 Chimeric receptor for use in whole-cell sensors for detecting analytes of interest INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-01-06 — — US disclosed
US-20250332186-A1 Methods and Compositions Relating to p62/SQSTM1 for the Treatment and Prevention of Inflammation-Associated Diseases CURELAB ONCOLOGY INC (US) 2025-10-30 — — US disclosed
US-20250249278-A1 METHODS FOR CONTROLLING THE TUMOR CELL KILLING BY LIGHT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-08-07 — — US disclosed
US-20250235492-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING TEAR FILM COMPOSITION TO TREAT CORNEAL DEFECTS CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (FR) 2025-07-24 — — US disclosed
US-12343376-B2 Methods for inhibiting diazepam binding protein Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-01 — — US disclosed
CN-118949941-A Nanopore assembly and uses thereof 牛津纳米孔科技公开有限公司 2024-11-15 — — CN disclosed
WO-2001042304-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-RELATED MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 — — WO disclosed
WO-2001011050-A1 Fhm, A NOVEL MEMBER OF THE TNF LIGAND SUPERGENE FAMILY AMGEN INC. (US) 2001-02-15 — — WO disclosed
WO-2001007074-A1 VGF SELECTIVE BINDING AGENTS AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 — — WO disclosed
WO-2001007477-A1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 — — WO disclosed
WO-2000074635-A2 DELIVERY OF SINGLE STRANDED DNA FOR EXPRESSION MIRUS CORPORATION (US) 2000-12-14 — — WO disclosed
EP-0848758-A1 TARGETED NUCLEOTIDE SEQUENCE DELIVERY AND INTEGRATION SYSTEM Avigen, Inc. (US) 1998-06-24 — — EP disclosed
WO-1998025630-A1 TRANSALDOLASE-MEDIATED REGULATION OF APOPTOSIS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-06-18 — — WO disclosed
WO-1997009442-A1 TARGETED NUCLEOTIDE SEQUENCE DELIVERY AND INTEGRATION SYSTEM AVIGEN, INC. (US) 1997-03-13 — — WO disclosed
WO-1995004064-A9 POLYNUCLEOTIDE DECOYS THAT IHNIBIT MHC-II EXPRESSION AND USES THEREOF — 1995-03-09 — — WO disclosed
WO-1994004548-A1 CHEMICALLY REVERSIBLE APTAMERS GILEAD SCIENCES, INC. (US) 1994-03-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097094-A1 METHODS FOR INHIBITING DIAZEPAM BINDING PROTEIN DBI, MAP1LC3B, BECN1 LPO 1821/4885MEN1 3542/4885KMT2A 2929/4885
US-12539510-B2 Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge DNMT3A, DNMT1, NSUN2 LPO 4875/4885MEN1 2327/4885KMT2A 302/4885
US-20250249278-A1 METHODS FOR CONTROLLING THE TUMOR CELL KILLING BY LIGHT TNFRSF9, CD47, CD4 LPO 3386/4885MEN1 3524/4885KMT2A 1592/4885
US-12638452-B2 Nanopore assemblies and uses thereof FAM83A, SCNN1G, SCN3A LPO 899/4885MEN1 2372/4885KMT2A 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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