Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980817 | 0.73 | HTR7 (0.50) | USP30UCHL1ERCC5FEN1HTR7 | |
| SCHEMBL17107113 | 0.72 | RAB9A (0.52) | USP30UCHL1HSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL1491198 | 0.72 | CHRNB2 (0.46) | ALDH1A1HPGDRAB9AHDAC1LMNA | |
| SCHEMBL4758491 | 0.71 | USP30 (0.44) | USP30UCHL1KDRHSD17B1HSD17B2 | |
| SCHEMBL22988620 | 0.70 | HTR7 (0.44) | USP30UCHL1ERCC5FEN1HTR7 | |
| SCHEMBL27554467 | 0.70 | KDR (0.44) | USP30UCHL1ERCC5FEN1KDR | |
| SCHEMBL25139544 | 0.68 | ERCC5 (0.53) | USP30ERCC5FEN1HTR7KDR | |
| SCHEMBL27572553 | 0.67 | MLYCD (0.47) | USP30ERCC5FEN1KDRCCNE1 | |
| SCHEMBL18620839 | 0.66 | KDR (0.50) | USP30ERCC5FEN1KDRCCNE1 | |
| SCHEMBL24092052 | 0.66 | KDR (0.44) | ERCC5FEN1HTR7KDRCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102472-A1 | METHODS AND COMPOSITIONS RELATED TO TARGETING FFAR2 AND ILC3 POPULATIONS FOR THE TREATMENT OF A GASTROINTESTINAL DISEASE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-05-22 | — | — | WO | claimed |