SCHEMBL219657

SCHEMBL219657

c1csc(-c2c[nH]nn2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
ALDH1A1 P00352 8/20 0.50
HPGD P15428 5/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
NPC1 O15118 8/20 0.44
RAB9A P51151 8/20 0.44
HSD17B10 Q99714 6/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17655611 0.85 LTA4H (0.44) KDM4EALDH1A1HPGDMEN1KMT2A
Lysine SCHEMBL25408697 0.74 GSR (0.44) KDM4EALDH1A1KMT2ATDP1GAA
SCHEMBL87533 0.69
SCHEMBL2053519 0.69 KDM4E (0.52) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL1389231 0.68 HSP90AA1 (0.42) ALDH1A1RAB9AHSD17B10CYP1A2
SCHEMBL15135194 0.68 IMPDH2 (0.37)
SCHEMBL1949338 0.68 KDM4E (0.50) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2197897 0.67 ALDH1A1 (0.38) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL498897 0.67 KDM4E (1.00) KDM4EALDH1A1HPGDMEN1KMT2A
Benzothiophene SCHEMBL17963012 0.67 CSNK2A2 (0.35) KDM4EL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119771460-A C with Janus homogeneous structure3N5Photocatalyst, preparation method and application thereof 常州工学院 2025-04-08 CN claimed
US-20230416539-A1 SOLUBLE CORROSION RESISTANT SOL-GEL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-12-28 US claimed
US-11746245-B2 Soluble corrosion resistant sol-gel THE BOEING COMPANY (US) 2023-09-05 US claimed
CN-108885396-B Positive working photosensitive material 默克专利有限公司 2023-03-24 CN claimed
US-20220342308-A1 POSITIVE WORKING PHOTOSENSITIVE MATERIALS MERCK PATENT GMBH (DE) 2022-10-27 US claimed
CN-109844641-B Environmentally stable thick film chemically amplified resists 默克专利有限公司 2022-10-11 CN claimed
US-11385543-B2 Enviromentally stable, thick film, chemically amplified resist MERCK PATENT GMBH (DE) 2022-07-12 US claimed
EP-3666852-B1 ETCHING SOLUTION HAVING SILICON OXIDE CORROSION INHIBITOR AND METHOD OF USING THE SAME VERSUM MAT US LLC (US) 2022-01-05 EP claimed
EP-3847506-A1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL Merck Patent GmbH (DE) 2021-07-14 EP claimed
CN-108274019-B Synthesis method of luminescent gold nanoparticles with surface plasma resonance absorption property 华南理工大学 2021-06-08 CN claimed
CN-1296485-A Substituted indolealkanoic acids INST FOR PHARM DISCOVERY INC (US) 2001-05-23 CN claimed
EP-1066283-A2 SUBSTITUTED INDOLEALKANOIC ACIDS The Institutes for Pharmaceutical Discovery, Inc. (US) 2001-01-10 EP claimed
WO-2000032180-A2 ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUTED INDOLEALKANOIC ACIDS THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. (US) 2000-06-08 WO claimed
WO-1999050268-A2 SUBSTITUTED INDOLEALKANOIC ACIDS THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. (US) 1999-10-07 WO claimed
US-4939140-A ALDOSE REDUCTASE INHIBITORS PFIZER INC. (US) 1990-07-03 US claimed
CN-1035116-A Heterocyclic type oxo-2 guanidine-acetic acid PFIZER (US) 1989-08-30 CN claimed
EP-0322153-A2 Heterocyclic oxophtalazinyl acetic acids PFIZER INC. (US) 1989-06-28 EP claimed
US-4559335-A 3-Acylamino-1-carboxymethyloxy (or thio) carbonyl-2-azetidinones E. R. SQUIBB & SONS, INC. (US) 1985-12-17 US claimed
US-4551277-A 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid E. R. SQUIBB & SONS, INC. (US) 1985-11-05 US claimed
US-4094881-A Process for preparing triazolethiols SMITHKLINE CORPORATION (US) 1978-06-13 US claimed